Tylenol vs. Advil

Difference between Tylenol and Advil Tylenol and Advil are the two effective OTC or Over-The-Counter pain killers. Though,…

Difference between Tylenol and Advil

Tylenol and Advil are the two effective OTC or Over-The-Counter pain killers. Though, these are very popular pain relievers available and accessible in the market, both Tylenol and Advil differ from each other.


Tylenol’s active ingredient is acetaminophen and is claimed to be gastric-friendly. Normally, when you take medicine it disrupts the pH balance of your intestine resulting in nausea and an upset stomach. It also means that you do not have to be full; you can take it on empty stomach too.  Tylenol along with being gastric friendly is an antipyretic as well. Be it symptoms of colds, allergies, cough or flu, it relieves all.   Though, it’s an OTC yet one needs to be careful while taking them. Taking two or more acetaminophen product at the same time can lead to an overdose and sickness. The symptoms of an overdose only occur after 24 to 48 hours, so better be careful.


Advil, like Tylenol is a pain-killer as well and also, available, accessible and popular in market by its generic name ibuprofen. A non-steroidal anti-inflammatory drug, Advil is used to alleviate the symptoms of arthritis, migraines or primary dysmenorrheal.  It is the brainchild of Pfizer and was invented in 1984. Unlike Tylenol, it needs to be taken on full stomach.  It shouldn’t be taken with aspirin as it is less effective when taken in the combination due to the anti-platelet effect of low dose aspirin. Ibuprofen is very trusted and tried drug and has registered lowest number of incidences of digestive adverse drug reactions only in low doses, though. The drug is sold in 200 and 500 mg potency. One can take maximum dose of 1200 mg daily.

Difference between Tylenol and Advil

Some Tylenol products need the prescription of medical practitioner. It can also be used to relieve flu symptoms and fever and taken on an empty stomach.  On the contrary, Advil is to reduce the symptom of different body pains. One needs to be very moderate with their usage. And if, pain is not reducing even after two days, better check with doctor.


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